Novel reagents for detecting cannabinoids

Details Novel reagents for detecting cannabinoids Novel reagents for detecting cannabinoids

G - Physics

01

N

G01N 33/94 (2006.01) G01N 27/447 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2441189

In this disclosure, novel cannabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples. The cannabind-based tracer has lower affinity for antibodies to .DELTA.9~ -THC and is more effectively displaced when a THC containing sample is applied. This results in higher sensitivity.

L'invention porte sur de nouveaux traceurs ~ base de cannabinol servant dans des dosages immunologiques pour d~tecter les cannabino~des dans des pr~l­vements biologiques, et particuli­rement utiles dans les dosages ~ flux continu. L'invention porte ~galement sur le proc~d~ de synth­se de ces nouveaux traceurs et sur leur emploi dans des dosages immunologiques par fluorescence servant ~ d~tecter les cannabino~des dans des pr~l­vements biologiques.

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