C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A61K 38/46 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) C12N 15/16 (2006.01) C12Q 1/42 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2161229
A novel receptor-type protein tyrosine phosphatase-? (RPTP?) protein or glycoprotein and the DNA coding therefor is expressed in a wide variety of mammalian tissues. The RPTP? protein or glycoprotein may be produced by recombinant means. Antibodies to the protein, methods for measuring the quantity of the protein, methods for screening compounds, such as drugs, which can bind to the protein and inhibit or stimulate their enzymatic activity, are provided. Further, methods for inhibiting homophilic binding of Type II RPTP, especially RPTP? molecules are provided.
Fuchs Miriam
Sap Jan M.
Schlessinger Joseph
Ullrich Axel
Vogel Wolfgang
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
New York University
Osler Hoskin & Harcourt Llp
LandOfFree
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