A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/08 (2006.01) A61K 31/00 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/194 (2006.01) A61K 31/22 (2006.01) A61K 31/375 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2362787
Redox clamping agents which maintain cells in a selected redox state are provided. Also provided are methods of using the redox clamping agents to sensitize cells to chemotherapeutic agents such as antineoplastics, to inhibit hyperproliferation of cells and to stabilize the redox state of cells with abnormal fluctuations in their redox state.
L'invention concerne des agents de fixation d'oxydoréduction permettant de maintenir des cellules dans un état d'oxydoréduction donné. Cette invention concerne également des procédés d'utilisation de ces agents de fixation d'oxydoréduction destinés à sensibiliser les cellules à des agents chimiothérapeutiques comme les antinéoplasiques, de manière à inhiber l'hyperprolifération desdites cellules et à stabiliser l'état d'oxydoréduction des cellules dont l'état d'oxydoréduction fluctue de manière anormale.
Mermelstein Fred H.
Yurkow Edward J.
Borden Ladner Gervais Llp
Rutgers The State University
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