Novel retinoid conjugate compounds and methods for treating...

Details Novel retinoid conjugate compounds and methods for treating... Novel retinoid conjugate compounds and methods for treating...

C - Chemistry, Metallurgy

07

C

C07C 403/00 (2006.01) A61K 8/36 (2006.01) A61K 8/362 (2006.01) A61K 8/365 (2006.01) A61K 8/67 (2006.01) A61K 31/075 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) A61K 31/225 (2006.01) A61K 31/60 (2006.01) A61K 47/48 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2178964

Skin aging and related conditions can be effectively treated with a conjugate of a retinoid and a bioactive organic acid preferably selected from among alpha-hydroxy acids, beta-hydroxy acids, and keto-acids; preferred conjugates include retinyl glycolic ether and retinyl glycolate (as either the ester or reverse ester).

Selon l'invention, le vieillissement de la peau et des états associés peuvent être traités efficacement au moyen d'un composé conjugué constitué d'un rétinoïde et d'un acide organique bioactif choisi, de préférence, parmi les acides alpha-hydroxyliques, les acides béta-hydroxyliques, et les acides cétoniques. Les conjugués préférés contiennent de l'éther glycolique de rétinyle et du glycolate de rétinyle (en tant qu'ester ou ester inverse).

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