C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 57/26 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/38 (2006.01) C07C 47/45 (2006.01) C07C 47/548 (2006.01) C07C 57/42 (2006.01) C07C 69/608 (2006.01) C07C 69/618 (2006.01) C07C 233/10 (2006.01) C07C 403/20 (2006.01) C07D 213/55 (2006.01) C07D 333/24 (2006.01)
Patent
CA 2170227
Novel nonatetraenoic acid derivatives of the formula Image I wherein the dotted bond is optional and R1 and R2 are as defined in the specific ation selectively bind to retinoic acid X-receptors (RXR) have anti-acne acitvity and potentiate the activity of retinoids having RAR.alpha. activity.
Klaus Michael
Lovey Allen John
Mohr Peter
Rosenberger Michael
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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