C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/075 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2363945
Compounds of formula (I); wherein R¿1? = alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R¿2? = hydrogen or halogen; R¿3? = hydrogen, alkyl or halogen; R¿4?= NHR' or NHOR'', R' or R'' are identical or different and represent hydrogen, alkyl, alkenyl or alkynyl, aryl; R¿5?= hydrogen or O-alkyl; R¿6?= alkyl or CH¿2-?O-alkyl; R¿7?= hydrogen or alkyl or R¿6? et R¿7? form a cycle together with the carbon carrying them in addition to the addition salts thereof with bases. The compounds of formula (I) have antibiotic properties.
Les composés de formule (I): R1: alkyle, alkényle ou alkynyle, O-alkyle, O- alkényle ou O-alkynyle éventuellement substitué, éventuellement interrompu; R2 hydrogène ou halogène; R3: hydrogène, alkyle ou halogène; R4: NHR' ou NHOR'' R' ou R'' identiques ou différents représentent hydrogène, alkyle, alkényle ou alkynyle, aryle; R5: hydrogène ou O-alkyle; R6: alkyle ou CH2-O-alkyle; R7: hydrogène ou alkyle ou bien R6 et R7 forment ensemble avec le carbone qui les porte un cycle ainsi que leurs sels d'addition avec les bases. Les composés de formule (I) présentent des propriétés antibiotiques.
Demassey Jacques
Klich Michel
Musicki Branislav
Aventis Pharma S.a.
Novexel
Robic
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