C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/22 (2006.01) C07H 21/02 (2006.01) C12N 9/12 (2006.01) C12N 9/88 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2197777
The invention concerns a method for creating, identifying, and isolating ribozymes capable of binding a selected ligand and catalyzing a reaction involving the selected ligand. The method entails sequential selections for ligand binding molecules and catalytic molecules. The invention also includes novel ribozymes produced by these methods.
L'invention concerne une procédé permettant de créer, d'identifier et d'isoler des ribozymes pouvant fixer un ligand sélectionné et catalyser une réaction dans laquelle ledit ligand sélectionné est impliqué. Le procédé présenté comporte des sélections séquentielles de molécules fixant le ligand sélectionné et de molécules catalytiques. L'invention concerne également de nouveaux ribozymes produits selon ce procédé.
Lorsch Jon R.
Szostak Jack W.
Wilson Charles
Smart & Biggar
The General Hospital Corporation
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