C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) A01K 67/027 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2350080
There are provided proteins having amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8 and 10; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP2; an antibody against BSSP2; and a method for detecting BSSP2 in a specimen by using the antibody.
La présente invention concerne des protéines comprenant les séquences d'acides aminés représentées par les SEQ ID NOS : 2, 4, 6, 8 et 10 ; des protéines comprenant des séquences d'acides aminés dérivées de ces mêmes séquences d'acides aminés par suppression, substitution ou addition d'un ou de plusieurs acides aminés ; et des séquences de base les codant. On décrit également des animaux transgéniques non humains ayant un niveau d'expression altéré d'une sérine protéase BSSP2 ; un anticorps dirigé contre BSSP2 ; et un procédé de détection de BSSP2 dans un échantillon à l'aide dudit anticorps.
Kominami Katsuya
Mitsui Shinichi
Okui Akira
Uemura Hidetoshi
Yamaguchi Nozomi
Fuso Pharmaceutical Industries Ltd.
Kirby Eades Gale Baker
LandOfFree
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