C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/64 (2006.01) C12N 9/48 (2006.01)
Patent
CA 2425001
Novel proteins or polypeptides having significant sequence homology to DPPIV, nucleic acids coding therefor, cells which have been modified with such nucleic acid so as to express these proteins, antibodies to these proteins, screening methods for the discovery of new therapeutic agents which are inhibitors of the activity of these proteins or of related proteins, and therapeutic agents discovered by such screening methods, as well as new therapeutic treatments, are all provided.
L'invention concerne de nouveaux polypeptides ou protéines possédant une forte homologie de séquence avec la dipeptidylpeptidase IV (DPPIV), et par conséquent des acides nucléiques codant pour ces protéines, des cellules qui ont été modifiées par lesdits acides nucléiques pour exprimer lesdites protéines, des anticorps correspondant auxdites protéines, des méthodes de sélection destinées à découvrir de nouveaux agents thérapeutiques inhibiteurs de l'activation desdites protéines ou de protéines s'y apparentant, des agents thérapeutiques découverts par lesdites méthodes de sélection, ainsi que de nouveaux traitements thérapeutiques.
Akinsanya Karen O.
Junien Jean-Louis
Qi Steve
Riviere Pierre J. M.
Ferring Bv
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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