C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/24 (2006.01)
Patent
CA 2676686
The present invention relates to an isolated polypeptide which has sialidase activity, selected from the group consisting of: (a) a polypeptide which has an amino acid sequence which has at least 60% amino acid sequence identity with amino acids 1 to 407 of SEQ ID NO: 3; (b) a polypeptide which is encoded by a polynucleotide which hybridizes under low stringency conditions with (i) the nucleic acid sequence of SEQ ID NO: 1 or 2 which is at least 80% or 90% identical over 60, preferably over 100 nucleotides, more preferably at least 90% identical over 200 nucleotides, or (ii) a nucleic acid sequence complementary to the nucleic acid sequence of SEQ ID NO: 1 or 2.
La présente invention concerne un polypeptide isolé possédant une activité sialidase, sélectionné dans le groupe comprenant: (a) un polypeptide possédant une séquence d'acides aminés comportant au moins 60% de l'identité de la séquence d'acides aminés des acides aminés 1 à 407 de SEQ ID NO: 3; (b) un polypeptide qui est codé par un polynucléotide qui forme un hybride dans des conditions peu strictes avec (i) la séquence d'acides nucléiques de SEQ ID NO: 1 ou 2 qui est au moins à 80% ou 90% identique sur plus de 60, de préférence plus de 100 nucléotides, mieux encore à au moins 90% identique sur 200 nucléotides, ou (ii) une séquence d'acides nucléiques complémentaire de la séquence d'acides nucléiques de SEQ ID NO: 1 ou 2.
Dekker Petrus Jacobus Theodorus
Efimova Yulia M.
Van Dijk Albertus Alard
Dsm Ip Assets B.v.
Smart & Biggar
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