C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/655 (2006.01) C07C 233/82 (2006.01) C07C 271/22 (2006.01) C07D 263/16 (2006.01) C07D 305/14 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2119261
Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain- bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided. Methods of the invention are used for the preparation of compounds of the following formulas: Image
Chen Shu-Hui
Kucera David J.
Moniot Jerome L.
Poss Michael A.
Thottathil John K.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
Novel sidechain-bearing taxanes and intermediates thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel sidechain-bearing taxanes and intermediates thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel sidechain-bearing taxanes and intermediates thereof will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2083404