C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2251578
TRAF5 as a novel protein and a polypeptide as a part thereof; a DNA encoding these; an antisense oligonucleotide against the DNA; an anti-TRAF5 antibody; a vector containing the DNA; a transformant prepared by using the vector; processes for producing the TRAF5 and the polypeptide as a part thereof; methods of screening substances binding to the TRAF5 or the polypeptide, substances regulating the activities of the same, and substances regulating the expression of the same by using the TRAF5 and the polypeptide; novel substances obtained by the screening; and various remedies containing these substances as the active ingredient.
Cette invention concerne une nouvelle protéine TRAF5, un polypeptide en faisant partie, un ADN codant ces derniers, un oligonucléotide antisens dirigé contre l'ADN, un anticorps anti-TRAF5, un vecteur contenant l'ADN, ainsi qu'un transformant préparé à l'aide de ce vecteur. Cette invention concerne également des procédés de production de TRAF5 et du polypeptide qui en fait partie, ainsi que des procédés qui font appel à la TRAF5 et au polypeptide afin de filtrer des substances se liant à la TRAF5 ou au polypeptide, des substances régulant l'activité de ces derniers, et des substances régulant leur expression. Cette invention concerne enfin de nouvelles substances obtenues par ce filtrage, ainsi que divers remèdes contenant ces substances en qualité d'ingrédient actif.
Mochida Pharmaceutical Co. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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