Novel single unit carbapenem aminoglycoside formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 31/43 (2006.01) A61K 31/7036 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2737879

The present invention relates to pharmaceutical low dose, antibiotic combinations of two antibiotics selected from two different groups viz. a carbapenem and an aminoglycoside present as a single unit fixed low dose injection effective at very low concentrations for the treatment of bacterial/ multi- bacterial infections particularly suitable for neonates, children and other patients with low tolerance which are prone to serious fatal mixed multi bacterial infectious diseases where potential toxicity due to higher doses is a cause for concern.

La présente invention concerne des combinaisons antibiotiques pharmaceutiques à faible dose de deux antibiotiques choisis dans deux groupes différents, à savoir un carbapenem et un aminoglycoside, présents dans une solution injectable à faible dose fixe en une seule unité efficace à très faibles concentrations pour le traitement d'infections bactériennes/multibactériennes, particulièrement adaptées aux nouveaux-nés, aux enfants et à d'autres patients à faible de tolérance qui sont sujets à des maladies infectieuses multibactériennes mixtes fatales graves, dans les cas où une toxicité potentielle attribuable à des doses plus élevées est préoccupante.

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