C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) A61K 31/713 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01)
Patent
CA 2718765
The present invention provides chemically modified siRNA compounds that target RTP801 and pharmaceutical compositions comprising same useful for treating microvascular disorders, eye diseases, hearing impairment, neurodegenerative diseases and disorders, spinal cord injury and respiratory conditions.
Cette invention concerne des composés à base dARNsi modifiés par voie chimique qui ciblent RTP801, et des compositions pharmaceutiques comprenant ces composés et utilisées dans le traitement des affections microvasculaires, des maladies oculaires, de latteinte auditive, des maladies et des affections neurodégénératives, des lésions de la moelle épinière et des affections respiratoires.
Feinstein Elena
Kalinski Hagar
Mett Igor
Skaliter Rami
Quark Pharmaceuticals Inc.
Torys Llp
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