C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 223/32 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2637838
The present invention relates to novel solid forms of (4R)-1-[4-(2-chloro-5- fluorobenzoyl)amino-3-methoxybenzoyl]-1,2,3,5-tetrahydro-spiro[4H-1- benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid (formula (I)) useful for treating and/or preventing conditions such as diabetic nephropathy, renal disease, renal failure and congestive heart failure.
La présente invention concerne des formes solides d~acide carboxylique (4R)-1-[4-(2-chloro-5-fluorobenzoyl)amino-3-méthoxybenzoyl]-1,2,3,5-tétrahydro-spiro[4H-1-benzazépine-4,1'-[2]cyclopentène]-3'(formule (I)) utiles dans le traitement et/ou la prévention d'états tels qu~une néphropathie diabétique, une maladie rénale, une insuffisance rénale ou une insuffisance cardiaque congestive.
Huang Lian
Wu Wenju
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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