Novel solvate and crystalline forms of carbamoyl-cyclohexane...

Details Novel solvate and crystalline forms of carbamoyl-cyclohexane... Novel solvate and crystalline forms of carbamoyl-cyclohexane...

C - Chemistry, Metallurgy

07

D

C07D 295/135 (2006.01) A61K 31/495 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2687078

The present invention relates to novel solvate and crystalline forms of carbamoyl- cyclohexane derivatives and, more particularly, to novel solvate and crystalline forms of trans-l {4-[2-[4-(2,3-dichlorophenyl)-piperazin-l-yl]-ethyl]-cyclohexyl}-3,3-dimethyl- urea hydrochloride. Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described.

L'invention concerne un nouveau solvate et des formes cristallines de dérivés de carbamoyle-cyclohexane et, plus particulièrement, de nouveau solvat et des formes cristallines de chlorhydrate de trans-l{4-[2-[4-(2,3-dichlorophényl)-pipérazin-1-yl]-éthyl]-cyclohexyl}-3,3-diméthyl-urée. Des procédés pour la préparation de ces formes, des compositions contenant ces formes, et des procédés d'utilisation sont également décrits.

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