Novel specific caspase-10 inhibitors

Details Novel specific caspase-10 inhibitors Novel specific caspase-10 inhibitors

C - Chemistry, Metallurgy

07

C

C07C 311/16 (2006.01) A61K 31/18 (2006.01) A61P 3/10 (2006.01) C07C 311/17 (2006.01) C07C 311/29 (2006.01)

Patent

CA 2605748

The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.

L'invention se réfère aux composés représentés par la formule générale (I), dans laquelle R1, R2, R3, R4, R5, R6, i et j ont les notations données dans la revendication 1, et à l'utilisation de ces composés comme inhibiteurs de la caspase 10, en particulier dans le traitement de la rétinopathie diabétique.

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