Novel sphingoglycolipids and uses thereof

Details Novel sphingoglycolipids and uses thereof Novel sphingoglycolipids and uses thereof

C - Chemistry, Metallurgy

07

H

C07H 15/04 (2006.01) A61K 31/70 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2160566

The present invention relates to a sphingoglycolipid represented by the formula (I): Image wherein R1, R2 and R5 represent H or a specific monosaccharide; R3 and R6 represent H or OH, respectively; R4 represents H, OH or a specific monosaccharide; X denotes an integer from 19 to 23; R7 represents any one of the following groups (a) - (g): ( a ) - ( CH2 ) 11-CH3 , ( b ) - ( CH2 ) 12-CH3 . ( c ) - ( CH2 ) 13-CH3 , ( d ) - ( CH2 ) 9-CH ( CH3 ) 2 , ( a ) - ( CH2 ) 10-CH ( CH3 ) 2 , ( f ) - ( CH2 ) 11-CH ( CH3 ) 2 , ( g ) - ( CH2 ) 11-CH ( CH3 ) -C2H5 . The present invention also relates to a pharmaceutical comprising the sphingoglycolipid as an effective ingredient, particularly an anti-tumor agent, a bone marrow cell-proliferation-promoting agent and an immunostimulating agent.

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