Novel spiro¬2.4|heptane amino carboxy compounds and...

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 229/50 (2006.01) A61K 31/196 (2006.01) A61P 25/00 (2006.01) C07C 229/46 (2006.01)

Patent

CA 2407777

The present invention relates to therapeutically active novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof. Also provided is a method of preparing compounds of Formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

La présente invention se rapporte à de nouveaux composés spiro[2.4]heptane amino carboxy et à des dérivés de ces composés. L'invention se rapporte également à un procédé de préparation de composés représentés par la formule (I), et à des compositions pharmaceutiques comportant ces composés. Ces nouveaux composés jouent le rôle de modulateurs des récepteurs du glutamate métabotropique et, en tant que tels, s'avèrent utiles pour le traitement des maladies du système nerveux central liées au système récepteur du glutamate métabotropique.

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