C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07D 209/00 (2006.01) C07D 213/61 (2006.01) C07D 221/00 (2006.01) C07D 307/00 (2006.01) C07D 307/94 (2006.01) C07D 405/12 (2006.01) C07D 491/10 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2379103
Compounds of formula (I) wherein T, U, V and W represent independently nitrogen atom or optionally substituted methine group, where at least two of them represent the said methine group; X represents methine or nitrogen; Y represents optionally substituted imino or oxygen atom; and the like. Compounds of the present invention exhibit NPY antagonistic activities and are useful as agents for the treatment of various diseases related to NPY.
L'invention concerne des composés de formule générale (I) dans laquelle T, U, V et W représentent séparément un atome d'azote ou un groupe méthine éventuellement substitué, au moins deux d'entre eux représentant ledit groupe méthine; X représente méthine ou azote; Y représente un atome d'oxygène ou imino; et similaire. Les composés de l'invention possèdent des activités antagonistes de NPY et sont utiles en tant qu'agents pour le traitement de diverses maladies associées à NPY.
Fukami Takehiro
Haga Yuji
Ishihara Akane
Ishii Yasuyuki
Itoh Takahiro
Banyu Pharmaceutical Co. Ltd.
Msd K.k.
Torys Llp
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