C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/395 (2006.01) A61K 31/4523 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 11/06 (2006.01) A61P 19/10 (2006.01) A61P 25/28 (2006.01) C07D 207/16 (2006.01) C07D 211/66 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2385130
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
L'invention concerne des composés inhibiteurs réversibles de cathepsine S, K, F, L et B représentés par les formules (I), (II), (Ia) et (Ib), définis plus avant dans le corps de l'invention. Ces composés sont utiles pour le traitement des maladies auto-immunes. L'invention concerne également des procédés relatifs à la fabrication des composés en question.
Emmanuel Michel J.
Frye Leah L.
Hickey Eugene R.
Liu Weimin
Morwick Tina M.
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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