C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/06 (2006.01) A23K 1/00 (2006.01) A23K 1/16 (2006.01) A23L 1/30 (2006.01) A61K 31/352 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2362268
A novel substance that has the physiological activity of the aglycone of isoflavones and the physiological activity of the culture of the basidiomycetes with the physiological activities being synergistically enhanced, obtained by cultivating a basidiomycetes having a .beta.-glucosidase activity in a medium containing an isoflavone, a method for producing it, and food, feedstuff and medicine containing it. The substance of the invention is improved in the physiological effect of the aglycone of isoflavones and the physiological effect of the culture of the basidiomycetes, and is not only useful as an anti-tumor agent but also is useful for therapy and/or prevention of osteoporosis and also as an immune enhancement agent.
L'invention concerne une nouvelle substance qu'on obtient en cultivant un basidiomycète à activité bêta-glucosidase dans un milieu contenant une matière à base d'isoflavones. Cette substance comprend les aglycones des isoflavones et le produit de culture du basidiomycète, et allie l'activité physiologique synergétiquement améliorée des aglycones des isoflavones à l'activité physiologique du produit de culture du basidiomycète. L'invention concerne également des produits alimentaires, des pâtures et des médicaments contenant la substance de l'invention. Cette substance, parce qu'elle possède l'activité physiologique synergétiquement améliorée des aglycones des isoflavones et l'activité physiologique du produit de culture du basidiomycète, est utile non seulement comme agent antitumoral, mais également comme agent de traitement et/ou de prévention de l'ostéoporose ou comme immunostimulant.
Kosuna Ken-Ichi
Miura Takehito
Sun Buxiang
Yuan Lan
Amino Up Chemical Co. Ltd.
Sim & Mcburney
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