Novel substituted piperidines, pharmaceutical compositions...

Details Novel substituted piperidines, pharmaceutical compositions... Novel substituted piperidines, pharmaceutical compositions...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/5513 (2006.01) A61P 3/10 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2476031

The invention relates to substituted piperidines of general formula (I), wherein R, R2 to R5, A, X, Z and n have the meaning defined in claim 1, to their tautomers, their diastereomers, their enantiomers, their mixtures and salts, especially their physiologically acceptable salts with inorganic or organic acids or bases. Said piperidines have valuable pharmacological properties, particularly CGRP-antagonistic properties. The invention also relates to medicaments containing said compounds, to the use thereof and to a method for the production of said compounds.

La présente invention concerne des pipéridines substituées de formule générale (I), dans laquelle R, R?2¿ à R?5¿, A, X, Z et n sont tels que définis dans la revendication 1, leurs tautomères, leurs diastéreo-isomères, leurs énantiomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement tolérables contenant des acides ou bases inorganiques ou organiques, lesquelles pipéridines présentent des propriétés pharmacologiques intéressantes, notamment des propriétés antagonistes du peptide lié au gène de la calcitonine (CGRP). Ladite invention concerne également des médicaments contenant ces composés, leur utilisation et un procédé de production desdits médicaments.

Affiliated with

Also associated with

Rating

Novel substituted piperidines, pharmaceutical compositions... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel substituted piperidines, pharmaceutical compositions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel substituted piperidines, pharmaceutical compositions... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1528462