C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/08 (2006.01) A61K 31/205 (2006.01) A61K 31/343 (2006.01) A61K 31/381 (2006.01) A61K 31/4174 (2006.01) A61K 31/4178 (2006.01) A61K 31/4995 (2006.01) A61K 31/551 (2006.01) A61P 31/04 (2006.01) C07C 229/34 (2006.01) C07C 257/14 (2006.01) C07C 279/14 (2006.01) C07D 233/60 (2006.01) C07D 307/91 (2006.01) C07D 333/24 (2006.01) C07D 407/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2388076
This invention relates to novel substituted succinic acid metallo-.beta.-lac- tamase inhibitors which are useful potentiators of .beta.-lactam antibiotics. Accordingly, the present invention provides a method of treating bacterial infections in animals or humans which comprises administering, together with a b-lactam antibiotic, a therapeutically effective amount of a compound of formula (I), including pharmaceutically acceptable salts, prodrugs, anhydrides, and solvates thereof.
L'invention concerne de nouveaux inhibiteurs de métallo- beta -lactamases d'acide succinique qui sont des potentialisateurs utiles des antibiotiques beta -lactamine. L'invention concerne donc un procédé de traitement d'infections bactériennes chez l'animal ou chez l'homme qui consiste à administrer, avec un antibiotique beta -lactamine, une dose thérapeutiquement efficace d'un composé de la formule (I), y compris des sels, promédicaments, anhydrides et solvates pharmaceutiquement acceptables de celui-ci.
Balkovec James M.
Greenlee Mark L.
Olson Steven H.
Rouen Gregory P.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Novel substituted succinic acid metallo-beta-lactamase... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel substituted succinic acid metallo-beta-lactamase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel substituted succinic acid metallo-beta-lactamase... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1362097