Novel substituted sulfamide derivatives

Details Novel substituted sulfamide derivatives Novel substituted sulfamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 319/20 (2006.01) A61K 31/357 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2731295

The present invention is directed to novel substituted sulfamide derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives form in the treatment of anxiety and related disorders; bipolar depression and mania; depression; epilepsy and related disorders; epileptogenesis; glucose related disorders; lipid related disorders; migraine; obesity; pain; substance abuse and as neuroprotective agents. The present invention is further directed to a process for the preparation of the novel substituted sulfamide derivatives.

Cette invention concerne de nouveaux dérivés sulfamides substitués, des compositions pharmaceutiques contenant lesdits dérivés et lutilisation desdits dérivés dans le traitement de langoisse et des troubles associés ; la dépression bipolaire et la manie ; la dépression ; lépilepsie et les troubles associés ; lépileptogenèse ; les troubles associés au glucose ; les troubles associés aux lipides ; la migraine ; lobésité ; la douleur ; la toxicomanie et comme agents neuroprotecteurs. Linvention concerne par ailleurs un procédé de préparation des nouveaux dérivés sulfamides substitués.

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