Novel substituted thiophenepyrimidinone derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2590233

This invention relates to novel substituted thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17.beta.-hydroxysteroid dehydrogenase enzymes.

La présente invention a pour objet de nouveaux dérivés substitués de thiophènepyrimidinone, ainsi que leur application dans le domaine de la thérapie, plus particulièrement leur emploi dans le traitement prophylactique et/ou thérapeutique de maladies ou de troubles liés aux hormones stéroïdiennes, tels que les maladies ou les troubles liés aux hormones stéroïdiennes qui requièrent l'inhibition des enzymes 17.beta.-hydroxystéroïde déshydrogénases.

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