C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/04 (2006.01) A61K 31/7032 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07H 15/06 (2006.01)
Patent
CA 2362903
Novel sulfofucosylacylglycerol derivatives represented by General Formula (1): (see formula 1) where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a higher fatty acid. The derivatives represented by General formula (1) are useful as a DNA polymerase inhibitor and an anticancer agent.
L'invention porte sur de nouveaux dérivés du sulfofucosylacylglycérol de formule générale (1) dans laquelle R101 est un résidu acyle d'un acide gras supérieur, et R102 est H, ou un résidu acyle d'un acide gras supérieur. Ces dérivés (1) sont utiles comme inhibiteurs de la synthase de l'ADN et agents carcinostatiques.
Fujita Tatsuya
Masaki Kazuyoshi
Nakayama Kotaro
Ohta Keisuke
Sahara Hiroeki
Gowling Lafleur Henderson Llp
Toyo Suisan Kaisha Ltd.
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