C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 19/00 (2006.01) C12N 9/02 (2006.01) C12N 9/12 (2006.01) C12N 9/14 (2006.01) C12N 15/52 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2465283
The present invention relates to the field of DNA recombinant technology. More specifically, this invention relates to fusion proteins comprising an ATP generating polypeptide joined to a polypeptide that converts ATP into a detectable entity. Accordingly, this invention focuses on sulfurylase- luciferase fusion proteins. This invention also relates to pharmaceutical compositions containing the fusion proteins and methods for using them.
La présente invention se rapporte au domaine de la technologie de recombinaison d'ADN. Plus spécifiquement, l'invention concerne des protéines de fusion comprenant un polypeptide de production d'ATP couplé à un polypeptide qui convertit l'ATP en une entité détectable. En conséquence, l'invention se concentre sur des protéines de fusion sulfurylase-luciférase. L'invention a également pour objet des compositions pharmaceutiques contenant les protéines de fusion et des procédés d'utilisation de celles-ci.
Reifler Michael
Srinivasan Maithreyan
454 Corporation
454 Life Sciences Corporation
Ridout & Maybee Llp
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