C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/117 (2010.01) A61K 31/7088 (2006.01) A61K 39/39 (2006.01) A61P 37/02 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2693266
The invention relates to synthetic chemical compositions that are useful for modulation of Toll-Like Receptor (TLR)-mediated immune responses. In particular, the invention relates to agonists of Toll-Like Receptor 9 (TLR9) that generate unique cytokine and chemokine profiles.
L'invention concerne des compositions chimiques synthétiques qui s'utilisent pour moduler les réponses immunitaires exprimées par le récepteur de type Toll (TLR). En particulier, l'invention concerne des agonistes de récepteur 9 de type Toll (TLR9) qui génèrent des profils de cytokine et de chimiokine uniques.
Agrawal Sudhir
Kandimalla Ekambar R.
Lakshmi Bhagat
Putta Mallikarjuna Reddy
Wang Daqing
Benoit & Cote Associes Inc.
Idera Pharmaceuticals Inc.
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