Novel targeted compositions for diagnostic and therapeutic use

Details Novel targeted compositions for diagnostic and therapeutic use Novel targeted compositions for diagnostic and therapeutic use

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 9/127 (2006.01) A61K 41/00 (2006.01) A61K 47/24 (2006.01) A61K 47/48 (2006.01) A61K 49/22 (2006.01) C07C 235/72 (2006.01) C07F 9/10 (2006.01) C07K 7/00 (2006.01) C07K 14/47 (2006.01) C07K 14/75 (2006.01) C07K 14/755 (2006.01) A61B 8/00 (2006.01) A61B 17/22 (2006.01) A61N 7/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2428606

Novel targeted compositions which may be used for diagnostic and therapeutic use. The compositions may comprise lipid, protein or polymer gas-filled vesicles which further comprise novel compounds of the general formula L-P-T, wherein L comprises a hydrophobic compound, P comprises a hydrophilic polymer, and T comprises a targeting ligand which targets tissues, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The compositions can be used in conjunction with diagnostic imaging, such as ultrasound, as well as therapeutic applications, such as therapeutic ultrasound.

L'invention concerne de nouvelles compositions ciblées qui peuvent être utilisées à des fins diagnostiques ou thérapeutiques. Les compositions peuvent comprendre des vésicules lipides, protéiniques ou polymères remplies de gaz renfermant de nouveaux composés de formule L-P-T, où L comprend un composé hydrophobe, P comprend un polymère hydrophile et T comprend un liant de ciblage qui cible des tissus, des cellules ou des récepteurs, dont des cellules myocardiques, des cellules endothéliales, des cellules épithéliales, des cellules tumorales et le récepteur de la glycoprotéine GPIIbIIIa. Les compositions peuvent s'utiliser conjointement à l'imagerie diagnostique, telle que l'écographie, ainsi que dans des applications thérapeutiques, telles que l'écographie thérapeutique.

Affiliated with

Also associated with

Rating

Novel targeted compositions for diagnostic and therapeutic use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel targeted compositions for diagnostic and therapeutic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel targeted compositions for diagnostic and therapeutic use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1446322