C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2608093
To identify conserved and variable regions of the 16 S rRNA, an instant evolution experiment was performed on the entire 16 S rRNA. Analysis of these mutants identified regions that are required for function. These conserved sequences may be used as targets for pharmaceuticals that are taxonomically specific and which are refractory to the development of drug resistance.
Selon l'invention, afin d'identifier des régions conservées et variables de l'ARNr 16 S, une expérience d'évolution instantanée est effectuée sur la totalité de l'ARNr 16 S. L'analyse de ces mutants a permis d'identifier des régions qui sont requises pour fonctionner. Ces séquences conservées peuvent être utilisées comme cibles pour des produits pharmaceutiques qui sont spécifiques sur le plan taxonomique et qui sont réfractaires au développement de la pharmaco-résistance.
Gowling Lafleur Henderson Llp
Wayne State University
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