Novel therapeutic and diagnostic products and methods

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A01K 67/027 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61P 25/00 (2006.01) C12N 15/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2651846

The present invention relates to the use of p11 as a drug target as well as a tool for the diagnosis, treatment and development of p11/5-HT receptor related disorders. The invention further relates to p11 knock-out animals as well as p11 transgenic animals and their use as models for the development of novel psychotherapeutic agents, and to methods of diagnosis, prophylaxis and treatment of p11/5-HT receptor related disorders.

La présente invention concerne l'utilisation de p11 en tant que cible de médicament ainsi qu'en tant qu'outil pour le diagnostic, le traitement et l'apparition de troubles apparentés au récepteur p11/5-HT. L'invention concerne en outre des animaux knock-out p11 ainsi que des animaux transgéniques p11, et leur utilisation en tant que modèles pour la mise au point de nouveaux agents psychothérapeutiques ; l'invention concerne aussi des procédés de diagnostic, de prophylaxie et de traitement des troubles apparentés au récepteur p11/5-HT.

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