Novel thermosensitive liposomes containing therapeutic agents

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 31/337 (2006.01) A61K 47/24 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2704258

A thermosensitive liposome for the delivery of active agents and a composition thereof are disclosed, wherein the liposome comprises at least one phosphatidylcholine, at least one phosphatidylglycerol and at least one lysolipid, and the gel to liquid phase transition temperature of said liposome is from 39 0°C to 45°C.

La présente invention concerne un liposome thermosensible pour la délivrance d'agents thérapeutiques et une composition le comprenant, le liposome comprenant au moins une phosphatidylcholine, au moins un phosphatidylglycérol et au moins un lysolipide, et la température de transition de phase gel-liquide dudit liposome est comprise entre 39,0 °C et 45 °C.

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