Novel thioester derivatives of thiazolyl acetic acid and...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) C07D 501/00 (2006.01) C07D 501/06 (2006.01)

Patent

CA 2433783

The present invention provides novel thioester derivatives of thiazolyl acetic acid of the general formula (I), also, the invention provides a method for preparation of the thioester derivatives and reaction of the thioester derivatives with cephem carboxylic acids to produce cephalosporin antibiotic compounds having general formula (II).

La présente invention concerne de nouveaux dérivés thio-esters d'acide acétique de thiazolyl de formule générale (I). L'invention concerne également un procédé de préparation de ces dérivés thioesters et la réaction de ces dérivés thio-esters avec des acides carboxyliques céphèmes de manière à produire des composés antibiotiques de céphalosporine de formule générale (II).

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