Novel thyroid hormone .beta. receptor agonist

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/65 (2006.01) A61K 31/44 (2006.01) A61K 31/4418 (2006.01) A61K 31/443 (2006.01) A61K 31/4433 (2006.01) A61K 31/4439 (2006.01) A61P 1/16 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 5/14 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 17/00 (2006.01) A61P 25/24 (2006.01) A61P 43/00 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 401/10 (2006.01) C07D 405/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2758894

Provided is a heterocyclic derivative showing a thyroid hormone .beta. receptor agonist action, which is effective for the prophylaxis or treatment of the diseases relating to the action. A compound represented by the formula [I]: (see formula I) wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, and a medicament containing the compound as an active ingredient.

L'invention porte sur un dérivé hétérocyclique qui a une activité agoniste du récepteur ß de l'hormone thyroïdienne et, par conséquent, est efficace pour la prévention ou le traitement de maladies associées à l'activité. De façon spécifique, l'invention porte : sur un composé représenté par la formule générale [I] (dans laquelle chaque symbole est tel que défini dans la description) ou un sel pharmacologiquement acceptable de celui-ci; et sur une préparation pharmaceutique comprenant le composé comme principe actif.

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