C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 49/00 (2006.01) C07K 16/12 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 19/00 (2006.01) C12N 5/16 (2006.01) C12N 5/26 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2422828
The present invention provides monoclonal antibody-producing hybridomas designated 27.F7 and 27.B1. The invention provides a method of detecting TIP-2 antigen bearing cancer cells in a sample. The invention provides a method of detecting TIP-2 antigen on the surface of cancer cells. The invention provides a method for diagnosing cancer in a subject. The invention provides a method for delivering exogenous material to TIP-2 antigen-bearing cancer cells of a human subject. The invention provides a method for treating cancer in a human subject. The invention provides isolated peptides having the amino acid sequences Lys Leu Leu Gly Gly Gln Ile Gly Leu (SEQ. ID NO. ) and Ser Leu Leu Gly Cys Arg His Tyr Glu Val (SEQ. ID No. ). The invention provides a method for immunohistochemical screening of a tissue section for the presence of TIP- 2 antigen bearing cancer cells. The invention provides a kit for detecting the presence of TIP-2 antigen-bearing cancer cells. The invention provides a method for detecting the presence of TIP-2 antigen. The invention provides a method for immunohistochemical screening of tissue sections. The invention provides a method for monitoring progression of cancer wherein the cancer cells are TIP-2 antigen-bearing cells. The invention provides a method for diagnosing cancer associated with the expression of TIP-2.
La présente invention concerne des hybridomes produisant des anticorps monoclonaux appelés 27.F7 et 27.B1; un procédé de détection de cellules cancéreuses portant l'antigène TIP-2 dans un échantillon; un procédé de détection de l'antigène TIP-2 à la surface de cellules cancéreuses; un procédé de diagnostic du cancer chez un sujet; un procédé d'apport de matière exogène aux cellules cancéreuses portant l'antigène TIP-2 chez un sujet humain; un procédé de traitement du cancer chez un sujet humain; des peptides isolés comprenant les séquences d'acides aminés Lys Leu Leu Gly Gly Gln Ile Gly Leu (SEQ. ID NO. ) et Ser Leu Leu Gly Cys Arg His Tyr Glu Val (SEQ. ID No. ); un procédé de criblage immunohistochimique d'une partie de tissu pour rechercher la présence de cellules cancéreuses portant l'antigène TIP-2; une trousse utile pour détecter la présence de cellules cancéreuses portant l'antigène TIP-2; un procédé de détection de la présence de l'antigène TIP-2; un procédé de criblage immunohistochimique de parties de tissu; un procédé de surveillance de la progression du cancer dans lequel les cellules cancéreuses sont des cellules portant l'antigène TIP-2; et un procédé de diagnostic du cancer associé à l'expression de TIP-2.
Canfield Robert
Kalantarov Gary
Rudchenko Sergei
Trakht Ilya
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of Columbia University In The City Of New York
LandOfFree
Novel tumor-associated marker does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel tumor-associated marker, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel tumor-associated marker will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1766379