Novel tumor suppressor gene, hic-1

Details Novel tumor suppressor gene, hic-1 Novel tumor suppressor gene, hic-1

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2205414

Polynucleotide and polypeptide sequences encoding a novel tumor suppressor, HIC-1, are provided. Also included is a method for detecting a cell proliferative disorder associated with HIC-1. HIC-1 is a marker which can be used diagnostically, prognostically and therapeutically over the course of such disorders.

L'invention se rapporte à des séquences polynucléotidiques et polypeptidiques codant un nouveau suppresseur de tumeur, HIC-1, ainsi qu'à un procédé de détection de troubles de la prolifération cellulaire associés à HIC-1. HIC-1 est un marqueur pouvant être utilisé dans des procédés de diagnostic, prognostic et thérapeutique pendant la durée de ces troubles.

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