C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/19 (2006.01) A01K 67/027 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2477249
The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.
L'invention concerne de nouveaux polypeptides et de nouveaux variants de ces polypeptides de polypeptides GLM-R, et des molécules d'acides nucléiques codant ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes comprenant des séquences d'acides nucléiques et des molécules polypeptidiques chimériques comprenant les polypeptides de l'invention fusionnées à des séquences polypeptidiques hétérologues, des anticorps se liant aux polypeptides de l'invention et des procédés de production des polypeptides de l'invention. L'invention concerne encore des méthodes de détection d'agents de modulation de l'activité de GLM-R. L'invention concerne aussi des méthodes de diagnostic et de traitement de troubles caractérisés par la surabondance ou la sous-abondance de monocytes ou de macrophages.
de Sauvage Frederic J.
Ghilardi Nico P.
Goddard Audrey
Godowski Paul J.
Grimaldi Christopher J.
Dennison Associates
Genentech Inc.
LandOfFree
Novel type-1 cytokine receptor glm-r does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel type-1 cytokine receptor glm-r, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel type-1 cytokine receptor glm-r will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1382262