C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4184 (2006.01) A61K 45/06 (2006.01) C07D 401/04 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2442428
The present invention provides compounds of formula I[ ] and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inhibiting tyrosine kinase enzymes.
L'invention concerne des composés correspondant à la formule (I) et des sels pharmaceutiquement acceptables de ces composés. Lesdits composés inhibent les enzymes du type tyrosine kinase et peuvent donc être utilisés comme agent anticancéreux. Ces composés sont également utiles pour le traitement d'autres maladies qui peuvent être traitées par inhibition des enzymes du type tyrosine kinase.
Balasubramanian Neelakantan
Frennesson David B.
Liu Peiying
Sang Xiaopeng
Saulnier Mark G.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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