Novel unsaturated fatty hydroxy acid derivatives and the...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 59/42 (2006.01) A61K 31/20 (2006.01) A61P 17/00 (2006.01) A61Q 19/00 (2006.01) C07C 59/56 (2006.01)

Patent

CA 2626635

The invention relates to unsaturated fatty hydroxy acid derivatives of formula (I), wherein Rn is independent from each other H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom, R1 is H, F, Cl, Br or CF3, R is H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom and 3 = n = 14. Said derivatives is suitable for producing an anti-radical, anti-inflammatory and antipruritic dermocosmetologic composition and/or for treating keratinisation and pigmentation troubles and/or for improving healing.

La présente invention concerne des dérivés d'hydroxy-acides gras insaturés répondant à la formule générale (I) : dans laquelle : . Rn représentent indépendemment les uns des autres H ou un groupe alkyle linéaire ou ramifié comprenant de 1 à 6 atomes de carbone et étant éventuellement substitué par un atome d'halogène en particulier de fluor, . R1 représente H, F, Cl, Br ou CF3, . R représente H ou un groupe alkyle linéaire ou ramifié comprenant de 1 à 6 atomes de carbone et étant éventuellement substitué par un atome d'halogène en particulier de fluor, et . 3 <= n <= 14. Ces dérivés sont utiles pour la fabrication d'une composition dermocosmétologique anti-radicalaire, anti- inflammatoire, anti-purigineuse, et/ou destinée au traitement des troubles de la kératinisation et de la pigmentation, et/ou à améliorer la cicatrisation.

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