Novel use

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/535 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2447063

A method for the treatment and/or prophylaxis of conditions characterised by altered bowel function and/or visceral pain in humans or non-human mammals, which method comprises the administration of an effective, non-toxic and pharmaceutically acceptable amount of an NK3 receptor antagonist, wherein the condition characterised by altered bowel function and/or visceral pain is selected from certain irritable bowel syndrome conditions, functional abdominal bloating, functional constipation, functional diarrhea, other bowel conditions and functional abdominal pain.

L'invention concerne une méthode de traitement et/ou de prévention de troubles caractérisés par une modification de la fonction intestinale et/ou des douleurs viscérales chez les mammifères, y compris l'homme. Cette méthode consiste à administrer une dose pharmaceutiquement acceptable, non toxique et efficace d'un antagoniste du récepteur NK3. Le trouble caractérisé par une modification de la fonction intestinale et/ou des douleurs viscérales est sélectionné dans les pathologies suivantes : certains troubles associés à un syndrome du côlon irritable, ballonnements abdominaux fonctionnels, constipation fonctionnelle, diarrhée fonctionnelle et autres troubles intestinaux et douleurs abdominales fonctionnelles.

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