Novel use of...

A - Human Necessities – 61 – K

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Details

A61K 31/496 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2372668

1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine or a physiologically acceptable salt thereof is used for the manufacture of a medicament for the treatment of sub-type anxiety disorders chosen from the sub-types panic disorder with or without agoraphobia, agoraphobia, obsessive- compulsive spectrum disorders, social phobia, posttraumatic stress disorder, acute stress indication or generalized-anxiety disorder, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, anorexia and fibromyalgia. A preferred salt is 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride.

L'invention concerne la 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-pipérazine, ou un sel physiologiquement acceptable de celle-ci, destinée à être utilisée pour fabriquer un médicament permettant de traiter certains troubles anxieux d'un sous-type faisant partie des troubles paniques avec ou sans agoraphobie, l'agoraphobie, le spectre des troubles obsessionnels, la phobie sociale, les syndromes de stress post-traumatique, les signes de stress aigu ou les troubles d'anxiété généralisée, les maladies affectives bipolaires, les manies, la démence, les dysfonctionnements en rapport avec un produit, les difficultés sexuelles, les troubles de l'alimentation, l'obésité, l'anorexie, et la fibromyalgie. Un sel préféré est le chlorhydrate de 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-pipérazine.

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