Novel use of mifepristone and derivatives thereof as...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31/575 (2006.01) A61K 31/56 (2006.01) A61P 3/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2513717

The invention relates to a novel use of compounds having formula (I), including mifepristone (RU 486 or RU 38 486) and the derivative salts thereof, for the preparation of a medicament that can modulate (activate or inhibit) the Hedgehog protein signalling pathway, which is intended for the treatment of pathologies involving a tissue dysfunction linked to deregulation of said pathway.

La présente invention est relative à une nouvelle utilisation des composés de formule (I): incluant la mifépristone (RU 486 ou RU 38 486) et des sels dérivés, pour la préparation d'un médicament capable de moduler (activer ou inhiber) la voie de signalisation des protéines Hedgehog, destiné au traitement des pathologies impliquant un dysfonctionnement tissulaire lié à une dérégulation de cette voie tels que des tumeurs choisies parmi les tumeurs du tissu nerveux (médulloblastomes, tumeurs primitives neuroectodermiques, glioblastomes, méningiomes et oligodendrogliomes), les tumeurs cutanées (carcinomes basocellulaires, trichoépithéliomes), les tumeurs des tissus musculaires et osseux (rhabdomyosarcomes, ostéosarcomes) et les tumeurs d~autres tissus (rein, vessie) ; Des pathologies de type neuro-dégénératif et du diabète.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Novel use of mifepristone and derivatives thereof as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel use of mifepristone and derivatives thereof as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel use of mifepristone and derivatives thereof as... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1536071

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.