Novel use of uridine diphosphate glucose 4-epimerase

Details Novel use of uridine diphosphate glucose 4-epimerase Novel use of uridine diphosphate glucose 4-epimerase

C - Chemistry, Metallurgy

12

P

C12P 19/30 (2006.01) C12N 9/90 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2392463

The present invention relates to a new use of uridine diphosphate glucose 4-epimerase (also called uridine diphosphate galactose 4-epimerase), and a method of converting uridine diphosphate N- acetylglucosamine (UDP-GlcNAc) to uridine diphosphate N-acetylgalactosamine (UDP-GalNAc) by using the said enzyme. The process for producing UDP-GalNAc by using the uridine diphosphate glucose 4-epimerase and the UDP-GalNAc supply system according to the present invention are practical and efficient, and greatly beneficial to the industries.

L'invention se rapporte à une nouvelle utilisation de l'uridine-diphosphate-glucose 4-épimérase (également appelée l'uridine-diphosphate-galactose 4-épimérase). Elle se rapporte à un procédé de conversion de l'uridine-diphosphate N-acétylglucosamine (UDP-GlcNAc) en uridine-diphosphate N-acétylgalactosamine (UDP-GalNAc) à l'aide de l'enzyme décrite ci-dessus. Du fait de leur aspect pratique et de leur efficacité, le procédé de synthèse d'UDP-GalNAc au moyen de l'uridine-diphosphate-glucose 4-épimérase décrite ci-dessus et un système d'alimentation en UDP-GalNAc s'avèrent présenter une grande utilité industrielle.

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