Novel uses of porphyrin compounds

A - Human Necessities – 61 – K

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A61K 31/409 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2571558

The invention provides the use of a compound of Formula (I), or metallated derivative thereof, in the preparation of a medicament for killing or attenuating the growth of microorganisms by a method which does not comprise exposing the compound to a photodynamic therapy light source or a sonodynamic therapy ultrasound source Formula (I) wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4 and Z have meanings given in the description. Preferably, the microorganisms are selected from the group consisting off bacteria, mycoplasmas, yeasts, fungi and viruses.

L'invention concerne l'utilisation d'un composé représenté par la formule (I), ou un dérivé de celui-ci ayant subi une métallation, dans la préparation d'un médicament destiné à supprimer ou atténuer la croissance de micro-organismes, au moyen d'un procédé ne consistant pas à exposer le composé à une source lumineuse de thérapie photodynamique ou une source ultrasonore de thérapie sonodynamique. Dans la formule (I), X1, X2, X3, X4, Y1, Y2, Y3, Y4 et Z sont tels que définis dans le descriptif. De préférence, les micro-organismes sont choisis dans le groupe comprenant bactéries, mycoplasmes, levures, champignons et virus.

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