C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/775 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2218759
The present invention relates to variants of the human apoloprotein A-I comprising a cystein in position 151, the corresponding nucleic acids and the vectors containing them. It also relates to pharmaceutical compositions comprising said elements and their utilization, particularly in genic therapy.
La présente invention concerne des variants de l'apolipoprotéine A-I humaine comprenant une cystéine en position 151, les acides nucléiques correspondants et les vecteurs les contenant. Elle concerne également des compositions pharmaceutiques comprenant ces éléments et leur utilisation, notamment en thérapie génique.
Assmann Gerd
Benoit Patrick
Bruckert Eric
Denefle Patrice
Duverger Nicolas
Institut Pasteur de Lille
Rhone-Poulenc Rorer S.a.
Robic
Universite Pierre Et Marie Curie
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