Novel variants of green fluorescent protein, gfp

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 9/96 (2006.01) C12N 15/54 (2006.01) C12N 15/62 (2006.01) C12N 15/65 (2006.01) C12Q 1/48 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2232727

The present invention relates to fluorescent proteins derived from Green Fluorescent Protein (GFP) or any functional analogue thereof, wherein the amino acid in position 1 preceding the chromophore has been mutated to provide an increase of fluorescence intensity.

Cette invention a trait à des protéines vertes fluorescentes dérivées de la Protéine verte fluorescente (GFP) ou de tout autre analogue fonctionnel de celle-ci où l'acide aminé en position 1 précédant le chromophore a subi une mutation pour déboucher sur une fluorescence d'une plus grande intensité.

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