Novel vinyl carboxylic acid derivatives and their use as...

C - Chemistry – Metallurgy – 07 – C

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C07C 59/58 (2006.01) A61K 31/192 (2006.01) A61K 31/216 (2006.01) A61P 1/18 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07C 69/734 (2006.01) C07C 255/54 (2006.01) C07D 277/24 (2006.01) C07D 307/42 (2006.01) C07D 333/16 (2006.01)

Patent

CA 2452665

Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR.delta. suptype.

L'invention concerne de nouveaux composés représentés par la formule générale (I), l'utilisation de ces composés comme compositions pharmaceutiques, des compositions pharmaceutiques comprenant ces composés, et des méthodes de traitement utilisant ces composés et ces compositions. Les composés de l'invention peuvent être utilisés dans le traitement et/ou la prévention d'états pathologiques associés aux récepteurs activés proliférateurs du peroxysome (PPAR), en particulier au sous-type PPAR.delta..

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