Novel viral vector

Details Novel viral vector Novel viral vector

C - Chemistry, Metallurgy

12

N

C12N 15/866 (2006.01) A61K 39/015 (2006.01) A61K 39/145 (2006.01)

Patent

CA 2695894

The present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; and pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; and pharmaceuticals containing the recombinant baculovirus as an active ingredient.

La présente invention concerne un nouveau vecteur de transfert et un baculovirus de recombinaison, des procédés de production de ceux-ci et des produits pharmaceutiques contenant le baculovirus de recombinaison comme principe actif, utilisés comme médicaments préventifs ou thérapeutiques contre des maladies infectieuses telles que la malaria et la grippe. L'invention concerne de manière plus spécifique un vecteur de transfert de recombinaison pouvant exprimer un gène étranger fusionné avec un gène viral sous le contrôle d'un double promoteur, un baculovirus de recombinaison, des procédés de production de ceux-ci et des produits pharmaceutiques contenant le baculovirus de recombinaison comme principe actif.

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