Novel vitamin d analogues

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 401/00 (2006.01) A61K 31/59 (2006.01) A61K 31/70 (2006.01) C07F 7/18 (2006.01) C07F 9/144 (2006.01) C07H 15/207 (2006.01)

Patent

CA 2051418

Image in which n, m, R1 and R2 are as defined in the specification. Such compounds find use in both human and veterinary practice in the treatment and prophylaxis of autoimmune diseases (including diabetes mellitus), hypertension, acne, alopecia, skin ageing, imbalance in the immune system, inflammatory diseases, e. g. , rheumatoid arthritis and asthma as well as diseases characterized by abnormal cell differentiation and/or cell proliferation, e.g., psoriasis and cancer.

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